Cellular Adhesion and a little Acute Inflammation

Hey everyone!
I'm a huge fan of visual learning devices, and I find this video particularly helpful. The inflammation part is slight, but if you ever wondered "what the heck are they talking about?" in any kind of cellular/molecular biology class, this is a great tool to clarify some points. They rope you in the beginning showing leukocyte adhesion to the endothelial cell, then they stray away from the point for a few minutes but discuss some interesting concepts regarding the cell. And finally, at the end, they return to the inflammation discussion. They show I-CAM and its role in cell adhesion as well as the extravasation of the leukocyte below the endothelial layer, which is how atherosclerotic plaques are formed. Between this and lots of other diagrams that we've seen, I think we can get a pretty full picture of what's happening. Thanks, Harvard!

http://multimedia.mcb.harvard.edu/anim_innerlife.html

Also, in response to my own question from Monday regarding why I-CAM isn't upregulated in response to inflammatory stimuli: turns out that I-CAM1 is constitutively expressed and is not upregulated, whereas I-CAM2 is upregulated and has a huge role in stroke etiology. Those tricksters!